glutathione side effects cancer Glutathione-mediated nanomedicines for diagnosis and therapy What are the side effects

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Competitive NNMT (nicotinamide N-methyltransferase) inhibitor preventing nicotinamide from being diverted away from the NAD+ salvage pathway

J Pharmacol Exp Ther 311:99108 Clancy RM, Levartovsky D, Leszczynska-Piziak J, Yegudin J, Abramson SB (1994) Nitric oxide reacts with intracellular glutathione and activates the hexose monophosphate shunt in human neutrophils: evidence for S-nitrosoglutathione as a bioactive intermediary

Doses Per Vial 5mg vial: At 2.5mg/week = 2 weeks At 5mg/week = 1 week 10mg vial: At 2.5mg/week = 4 weeks At 5mg/week = 2 weeks At 7.5mg/week = 1.3 weeks At 10mg/week = 1 week 15mg vial: At 2.5mg/week = 6 weeks At 5mg/week = 3 weeks At 10mg/week = 1.5 weeks At 15mg/week = 1 week A 10mg vial covers the first month of a standard escalation at 2.5mg/week

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