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Free radicals formed during lipid peroxidation have a local effect due to short life, but the degradation products of lipid peroxidation can be second messengers of oxidative stress, because of their longer half-life and ability to diffuse from the place of formation

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Tirzepatide has been shown to significantly reduce inflammatory markers including hsCRP and IL-6 in clinical studies

however, it represents a benign, possibly reactive process

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