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Front Genet 12 , 774489 (2021)

In particular, metabolic diseases such as T2D promote early onset of muscle impairment by altering glucose homeostasis and anabolic signaling pathways

By slowing the rate at which food leaves the stomach, GLP-1 agonism extends the feeling of fullness after meals

Cost-effectiveness is not black and white, and accumulating data from real-world use could assist decision makers in making choices about coverage in the future