This article walks through what that evidence actually is, why no trial has started, and what would count as real progress
Reporting summary Further information on research design is available in the Nature Portfolio Reporting Summary linked to this article
Bioresour Technol 301:122698 Astuti IY, Suratman A, Lal B, Hosseini-Bandegharaei A, Zango ZU, Adamu H, Siswanta D (2025) Thiourea-modified chitosan for effective adsorption of Remazol Brilliant Blue R: Synthesis, characterization, adsorption properties, and morphological effects
Notably, 100% of participants in both the 8 mg and 12 mg groups achieved at least 5% body weight reduction, with 83% of the 12 mg group achieving reductions of 15% or more
Epidermal NAD+ deficiency induces IL-36-mediated skin inflammation and acanthosis [PMID: 41665963] Laboratory literature summary: Epidermal NAD+ deficiency induces IL-36-mediated skin inflammation and acanthosis