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A recent review in the Journal of Clinical Investigation summarized data showing that GLP-1based drugs reduce key inflammatory mediators and alter innate and adaptive immune responses across multiple organ systems

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PT-141 has undergone full Phase 3 clinical trials with over 1,200 subjects and received FDA approval as bremelanotide (Vyleesi) for female hypoactive sexual desire disorder in 2019, which means it has passed formal safety and efficacy review