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Opening and closing the refrigerator door repeatedly, storing vials in the door compartment where temperature swings are greatest, or placing vials near the back where they might freeze, all of these common habits affect shelf life
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1 Introduction Prader-Willi syndrome (PWS) is a rare genetic disorder characterized by impaired hypothalamic development and function with an estimated incidence of 1 per 20,000 newborns ( Patients with PWS experience complex nutritional, neurodevelopmental, metabolic and behavioral changes that drive obesity development ( Obesity management in PWS typically includes a calorie-restricted diet, strict control of food access, regular physical activity and behavioral interventions ( 2 Case series 2.1 Patient 1 A 28-year-old female with PWS, resulting from uniparental disomy, was evaluated at our Endocrinology Unit
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