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PLOS Biology
The hypothesis has expanded to include vascular dysfunction, oxidative stress, microglial activation, and impaired proteolysis (Roda et al., 2022)
He said: It is well established that better mental health tends to follow from better physical health and since the 1880s we have known that diabetes is associated with depression, although I think its unlikely that using GLP-1R agonists alone as treatments for depression or anxiety will work. Prof Eduard Vieta, a professor of psychiatry at the University of Barcelona and editor in chief of the European College of Neuropsychopharmacology journal, said: From a clinical perspective, these findings are reassuring regarding the psychiatric safety of GLP-1 receptor agonists and suggest a potential role not only in preventing worsening but also, possibly, in improving mental health outcomes
10.1038/s41576-022-00562-w Nat
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