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Here is what research has explored

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One of these studies demonstrated a 1.7-fold higher recovery of toxic metabolites in those with Gilberts syndrome compared to controls [33], although a larger study only found a higher rate of recovery of toxic metabolites in those patients stratified by having the lowest UGT activity [28]

However, these findings are preliminary, and glutathione is not FDA-approved or medically recommended for skin lightening

Feb 2010;35(1):101-5