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So why weight loss

It improves insulin sensitivity and nutrient partitioning, directing calories toward muscle rather than fat storage

The Milken Institute's geographic mapping of Phase 2 and 3 trial sites found that counties more than 60 miles from a trial site tend to have lower incomes and education levels, less internet access, and higher rates of disability, and that agricultural counties and American Indian reservations are disproportionately far from trial access points ( [89] )

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People do best on the medications when they make healthy diet changes and get regular physical activity