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In clinical trials targeting obese populations, Survodutide demonstrated varying degrees of weight loss across dosages ranging from 0.6 to 4.8 milligrams
Doctors typically look for a doubling time under 72 hours for this range
This variability is influenced by differences in the permeability of the bloodbrain barrier (BBB) and the bloodcerebrospinal fluid (CSF) barrier, as well as by region-specific expression of enzymes involved in glutathione metabolism
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