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The lyophilized state prevents hydrolytic degradation and maintains peptide bond integrity
But can they afford not to
Bharti Sharma, Lee Schmidt, Cecilia Nguyen, Samantha Kiernan, Jacob Dexter-Meldrum, Zachary Kuschner, Scott Ellis, Navin D
Entero-endocrine-osseous axis : gastrointestinal hormones as substrates for DPP-4 The initial observation that patients receiving long-term parenteral nutrition develop osteoporosis and osteomalacia raised suspicion about the lack of stimulation for the secretion of incretin hormones in this mode of nutrition and a potential connection between these hormones and bone metabolism [42]
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