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Similarly, a significant elevation was measured in the permeability of targeted ibuprofen-coupled nanocarrier 3-PLG-ibu-A-GSH (P app : 27.70 10 6 cm/s) compared to the non-targeted 3-PLG-ibu (P app : 8.29 10 6 cm/s) polypeptide in the 24-h assay (Fig

Loss of SLC25A39 reduces mitochondrial GSH import and abundance without affecting cellular GSH levels

black squares) or acyl-GIP (100nmol/kg

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Document History Version: V 1.0 Author: SWL ICB Approved by: Integrated medicines committee (IMOC) Approval date: 16/11/2022 Review Date: 2 years from approval date or sooner where appropriate