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The NRF2 and NRF1 pathways regulate GPX4 expression, with NRF2 downregulation elevating GPX4 levels and NRF1 enhancing GPX4 expression to inhibit ferroptosis
Bakken TE, Miller JA, Ding S-L, Sunkin SM, Smith KA, Ng L, Szafer A, Dalley RA, Royall JJ, Lemon T, Shapouri S, Aiona K, Arnold J, Bennett JL, Bertagnolli D, Bickley K, Boe A, Brouner K, Butler S, Byrnes E, Caldejon S, Carey A, Cate S, Chapin M, Chen J, Dee N, Desta T, Dolbeare TA, Dotson N, Ebbert A, Fulfs E, Gee G, Gilbert TL, Goldy J, Gourley L, Gregor B, Gu G, Hall J, Haradon Z, Haynor DR, Hejazinia N, Hoerder-Suabedissen A, Howard R, Jochim J, Kinnunen M, Kriedberg A, Kuan CL, Lau C, Lee C-K, Lee F, Luong L, Mastan N, May R, Melchor J, Mosqueda N, Mott E, Ngo K, Nyhus J, Oldre A, Olson E, Parente J, Parker PD, Parry S, Pendergraft J, Potekhina L, Reding M, Riley ZL, Roberts T, Rogers B, Roll K, Rosen D, Sandman D, Sarreal M, Shapovalova N, Shi S, Sjoquist N, Sodt AJ, Townsend R, Velasquez L, Wagley U, Wakeman WB, White C, Bennett C, Wu J, Young R, Youngstrom BL, Wohnoutka P, Gibbs RA, Rogers J, Hohmann JG, Hawrylycz MJ, Hevner RF, Molnr Z, Phillips JW, Dang C, Jones AR, Amaral DG, Bernard A, Lein ES (2016) A comprehensive transcriptional map of primate brain development
Neuromodulators are used in facial contouring to relax specific muscles, which can help slim the jawline, lift and shape the eyebrows, reduce a square jaw appearance, soften chin dimpling, perform a lip flip, and enhance cheekbones by relaxing muscles that pull the face downward, thus providing a more sculpted and balanced facial appearance
"Propofol: A dangerous kind of rest"
doi: 10.1007/s12551016-02444 260 El-MahroukSREl-GhiatyMAEl-KadiAOS
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