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This metabolic reprogram can initially deplete energy reserves, especially if calorie intake drops too quickly or nutritional intake becomes unbalanced
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107,108 In ME2-unexpressed gastric cancer cells, its isoenzyme ME1 is upregulated to replenish intracellular NADPH and promotes cell survival under glucose starvation and anoikis
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MT-2's effects on pigmentation can persist for months, but hormonal and cardiovascular markers should normalize relatively quickly
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