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Glutathione oxidation by hypochlorous acid in endothelial cells produces glutathione [PMID: 11283008] Laboratory literature summary: Glutathione oxidation by hypochlorous acid in endothelial cells produces glutathione sulfonamide as a major product but not glutathione
A study by Wierdsma et al
Recently identified derivatives of bile acids (called tertiary bile acids), have shown the ability to act simultaneously on GPBAR and also on RORt on which some of them exert an inverse agonist activity
After derivatization with 10 l of 5 mM 7-diethylamino-3-(4-maleimidophenyl)-4-methylcoumarin (Sigma-Aldrich) at room temperature for 10 min, the maleimide ring was cleaved by addition of 30 l of 50 mM ammonium formate (Sigma-Aldrich) pH 4.2 at room temperature for another 30 min
Effects of empagliflozin on renal sodium and glucose handling in patients with acute heart failure
