While the FDA-approved prescribing information does not list hyperhidrosis or increased perspiration as a recognized adverse effect of Zepbound, some patients report changes in sweating patterns during treatment
Challenges include gastrointestinal side effects, nutritional deficiencies due to calorie reduction, muscle and bone loss, low long-term adherence with subsequent weight regain, and high costs, resulting in low cost-effectiveness
Fabrini R, De Luca A, Stella L, Mei G, Orioni B, Ciccone S et al
2025 Mar 1:351:123123
Investigadores de Yale University, el Kings College Hospital de Londres y la organizacin sin nimo de lucro Mdicos Sin Fronteras han publicado en la revista JAMA Network Open un informe segn el cual el medicamento podra producirse por entre 89 cntimos y US$4,73 al mes, cantidades que tienen en cuenta el margen de ganancia