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OxPhos is achieved in the presence of saturating ADP levels and the sequential addition of different mitochondrial substrates, including pyruvate, malate, glutamate (N-linked, through complex I) and succinate (S-linked, through complex II)

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In cases of deficiency: anaemia, digestive, neurological and psychological disorders Anaemia, characterized by insufficient iron in the blood, occurs frequently in people with a vitamin B12 deficiency

An experimental study of a Mediterranean diet intervention for patients with rheumatoid arthritis