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A case for screening real-world data for collateral drug benefits: Glucagon-like peptide 1 receptor agonists and bile acid diarrhea

So, for example, during expression and purification of a recombinant protein, it may have a disulfide bond form, which wouldnt normally form in the proteins natural context

Exp Mol Med (2016) 48:e2244

Strong connections were observed between vomiting and nausea, pancreatitis and GI distress, and depression and anxiety, highlighting patterns of symptom overlap among users

Participants were randomized to receive either the glutathione supplement or placebo capsules and were evaluated every four weeks over a 12-week study period