Orforglipron is the first oral, non-peptide, small-molecule GLP-1 RA to be approved
Understanding these mechanisms helps you make better decisions about diet, dose timing, and side effect management, and makes your tracking data more meaningful
A popular dual agonist, tirzepatide (Mounjaro), activates both GLP-1R and GIPR, producing synergistic effects on insulin secretion, appetite suppression, and weight reduction (Table 1)
Crucial NITs in NAFLD patients stratification are especially the fibrosis-4 (FIB-4) - an index that takes into account age, transaminases and platelet count- and the liver stiffness evaluation by VCTE
Recent Updates November 21, 2025: Changed the price of Sheds optional coaching program from $70 to $49.99