One meta-analysis of more than 47 studies estimated that people taking metformin had a 30% lower overall risk of cancer compared to those using other diabetes medications
As a result, you tend to eat more food and may eat more often than you did while on the drug
Fifth Meething of the International Society of Haematology 1:91, 1979
These include the following: therapeutic benefits resulting from non-antioxidant mechanisms, insufficient dosage to elicit an antioxidant effect, poor oral bioavailability, a narrow therapeutic index, or toxicity that precludes clinical use
Notably, this pathway can be reversed by activating YAP1 through MST1/2 inhibition, which shifts macrophages from an M2 to an M1 phenotype, enhancing CD8+ T-cell activity and mitigating tumor progression