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McCullough KD, Martindale JL, Klotz LO, Aw TY, Holbrook NJ

The study found that 5-amino-1MQ effectively slowed the growth of these cancer cells and even led to signs of cell death (apoptosis)

To identify the specific effects of ferroptosis on ESCs, primary ESCs were treated with several ferroptosis inducers, such as erastin (30 M), (1S,3R)-RSL3 (10 M), tert-butyl hydroperoxide solution (TBHP, 20 M), diluted cyst fluid (1:1 dilution with complete medium), and with inhibitor NAC (10 M) for 12 h