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L., Wang, L
In some individuals, usually adults, acetaminophen can induce a high-anion-gap metabolic acidosis secondary to 5-oxoproline (ie, acquired pyroglutamic academia), possibly because of a genetically determined propensity (54
Medications like semaglutide are GLP-1 receptor agonists, meaning they mimic the effect of GLP-1 but stay active longer and produce a stronger, more sustained signal
This reduction in ROS might be crucial, as oxidative stress is considered a key factor in cellular aging
2.3.2 Disulfide stress-related Rac1-WRC-Arp2/3 signaling pathway Rac1 (a type of Rho GTPase), a fundamental regulatory factor of the actin cytoskeleton, plays important roles in cell movement, polarity, and migration (Bailly et al., 2024)
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