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Despite the results, researchers emphasized that the study was observational and cannot prove cause and effect
The activation phase necessitates various intracellular stimuli (e.g., K + efflux, Ca 2+ mobilization, mitochondrial ROS, or lysosomal rupture) to trigger NLRP3 oligomerization
[5] While copper can potentially cause skin irritation or toxicity, in vitro studies suggest that GHK-Cu complexes may have a lower likelihood of inducing these effects
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