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Moreover, the SFN-mediated decrease in CD25 and CD69 expression was not restored by addition of IL-2 (Supplementary Figure 3)

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Nutritional considerations are also important, as the appetite-suppressing effects of semaglutide may lead to inadequate protein intake or micronutrient deficiencies, particularly during significant weight loss

The addition of vitamin B12 aids in the treatment tolerance of GLP-1 agonists like semaglutide

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