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465 The anterior cingulate cortex, essential for emotional pain processing, shows increased blood flow in patients with PDPN, a hyperperfusion state that normalizes following duloxetine treatment
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In addition to OCTN2, organic cation transporter 1 (OCT1, SLC22A1) can also promote the hepatic efflux of acetylcarnitine and contribute to the plasma acetylcarnitine pool [60]
The findings suggest that targeted antioxidant supplementation could be useful when older adults with sarcopenia start structured resistance training, particularly if their baseline vitamin status is poor
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