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[13] [14] Patients with a personal or family history of medullary thyroid carcinoma or multiple endocrine neoplasia syndrome type 2 should not receive GLP-1 medications due to the theoretical risk of thyroid C-cell tumors

Same protocol, same duration, same titration rules, 751 adults randomized 1:1

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TRIUMPH-1 reported mean body weight reduction of 28.3% at 80 weeks on the 12 mg arm