These include: Lifestyle interventions (dietary advice, physical activity programmes) Licensed pharmacotherapy such as orlistat, or GLP-1 receptor agonists including semaglutide 2.4 mg (Wegovy, NICE TA875) or tirzepatide (Zepbound) where clinically indicated and available Referral to tier 3 or tier 4 weight management services , including bariatric surgery assessment where appropriate Information on NHS weight management services and eligibility for licensed treatments is available via the NHS website and NICE guidance
Baseline labs such as CMP or IGF-1 help ensure safe prescribing and allow us to monitor your progress responsibly
As you get older, the systems that rely on NAD+ (like energy production, cognitive function, skin repair, immune health, and inflammation regulation) start to slow down, and declining NAD+ levels appear to be a key driver behind that slowdown
Like our other picks in this guide, Perpetua.Lifes urolithin A supplement is third-party tested for safety and potency
Neuroscientific research has further examined the peptides interaction with monoaminergic pathways, particularly those involving dopamine and serotonin signaling