tirzepatide to semaglutide conversion and equivalent doses For the first time, were put in the same trial. SURMOUNT-5. Phase 3b RCT. 751 adults with obesity, no Switching from semaglutide to tirzepatide

For glycemic control, a published comment concluded that tirzepatide microdosing at 2.5 mg resulted in a 15% reduction in HbA1c levels, indicating metabolic improvement even at modest exposures, as noted in a comment by Kom et al

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