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Fagher, B., Cederblad, G., Monti, M., Olsson, L., Rasmussen, B., and Thysell, H

That said: Long-term use should be structured, not random Periodic breaks or reassessment are sensible Quality of formulation matters more than duration Clinically formulated products like Glutone 1000 are designed for sustained use without unnecessary overload

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The key is whether the date, lot, product, and size all point to the same submitted sample

Common approaches include continuous use, 5-days-on/2-days-off schedules, or cycling (e.g., 8-12 weeks on, 2-4 weeks off)