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Severe or prolonged diarrhea can interfere with medication absorption and nutrient uptake, potentially reducing treatment effectiveness and overall health
Problems with large vessels include strokes and heart attacks
Joel Lexchin, retired physician and professor emeritus at the school of health policy and management at York University, said data on the drug's long-term effectiveness is too limited
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Escin, an active saponin in the horse chestnut seed, appears to have weak diuretic activity, but the exact mechanism is not clear
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