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Its intracellular depletion ultimately results in cell death, and its clinical relevance has been researched for decades
Depressive symptoms and increased anxiety due to diabetes-related distress (i.e., the emotional and psychological burden associated with managing diabetes [140] are associated with poor self-care behaviors and worse intermediate and long-term health outcomes [218]
Some protocols may use post-workout timing to maximize nutrient partitioning to muscle tissue
Alternative strategies: intermittent dosing and drug holidays An emerging area of clinical interest is whether intermittent dosing or planned drug holidays can reduce cost and side effects while maintaining weight loss
Hinds M, et al
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