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Palazzo M, Balsari A, Rossini A, Selleri S, Calcaterra C, Gariboldi S, et al
Because of its dosing consistency, it is typically ideal for acute concerns or structured protocols
avoid freezing and excessive heat
Just like we dont consider and/or for the four pillars of guideline-directed medical therapy for heart failure with reduced ejection fraction, we shouldnt parcel out these two therapeutic optionsit should be both. Setting expectations with your patients regarding injection practices, side effects, and expected benefits can go a long way toward improving the patient experience with GLP-1 RAs
Hendershot et al., "Once-Weekly Semaglutide in Adults With Alcohol Use Disorder: A Randomized Clinical Trial," JAMA Psychiatry , April 2025
