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Shel making a tiny incision, either in the buttock or hip, and then using a specialized tool to insert the pellet
2006;291(6):E1290-E1297
[0010] In some particular embodiments of the present invention, the fully-protected fragment of Fmoc-PEG-PEG--Glu-octadecanedioic acid used in the fragmental synthesis of the Lys 26 side chain in the preparation method is prepared by successively coupling a chloride resin to Fmoc-PEG-OH, Fmoc-PEG-OH, Fmoc-Glu(OH)-OtBu and Octadecanedioic Acid mono-tert-butyl ester, cleaving, and recrystallizing to obtain PEG-PEG--Glu-Octadecanedioic Acid mono-tert-butyl ester
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