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Loss of TALDO reduces GSH and diminishes -catenin phosphorylation and Fas-dependent apoptosis, promoting hepatocarcinogenesis in mouse models (113)

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Because amylin signalling is closely linked to meal termination, satiation, and brainstemhypothalamic regulation of food intake, amylinGLP-1 co-agonism may reshape eating experience through mechanisms that partly overlap with, but are not identical to, classical GLP-1R agonism

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