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Bardoxolone has met the primary endpoint and critical secondary endpoint in a Phase 3 study for the treatment of patients with Alport Syndrome (AS)-associated chronic kidney disease, significantly improving patients' estimated glomerular filtration rate (eGFR)
Human clinical data remains limited, with ongoing trials evaluating broader applications
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doi: 10.1007/BF02714149 9 CantoniO.SestiliP.PalombaL.GuidarelliA.CattabeniF.MurrayD
A: Yes, modestly
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