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The glucagon receptor activation that some researchers worried might raise cardiovascular risk has not produced adverse effects in human trials
2011 May;34(Suppl 2):S279-84.
It has also given rise to concerns about counterfeit drugs that may be circulating on the market, as well as the safety and efficacy of the compounded semaglutide produced by compounding pharmacies
And it didnt find a difference, albeit the study was small, I think it was twenty four patients
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