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Native amylin is notoriously difficult to work with because it aggregates to form amyloid fibrils (a property exploited by the pancreatic amyloid deposits seen in T2D progression)
The cyclical dosing protocols used in research (short cycles followed by long breaks) inherently limit total exposure
However, more research is necessary to confirm these benefits.
Owing to its liposoluble and isomeric characters, lycopene is more bioavailable in processed tomato products such as ketchup than in raw tomatoes, especially when the carotenoid is processed with oil (Tan et al., 2010)
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