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As demonstrated by Feetham CH et al., acute activation of BDNF neurons in the medial nucleus of the tractus solitarius reduces food intake and promotes fatty acid oxidation, potentially contributing to sustained weight loss (49)
Wilding JP, Overgaard RV, Jacobsen LV, Jensen CB, le Roux CW
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Moreover, miR-155 may influence fatty acid accumulation by targeting CCAAT/enhancer-binding protein (C/EBP) in HepG2 cells
Some patients report residual mild discomfort that persists longer, but severe pain that does not improve after two months warrants medical evaluation to rule out other causes
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