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Nonsteroidal anti-inflammatory drugs (NSAIDs) target and inhibit cyclooxygenase (COX), thereby blocking the COX-mediated metabolism of arachidonic acid (AA)

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Fibroblast growth factor 21 protects against acetaminophen-induced hepatotoxicity by potentiating peroxisome proliferator-activated receptor coactivator protein-1-mediated antioxidant capacity in mice