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Supplementation with B vitamins, iron (if deficient), and electrolytes can also help

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It also intensifies the nausea and GI side effects of tirzepatide

Phase III involves the transport of these metabolites by transporters, after which they are eliminated through bile or urine, preventing potential adverse effects on the liver

However, further studies are warranted to fully delineate the distinct pathophysiology of MetALD development, which is driven by both alcohol and metabolic dysfunction