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The aberrant activation of self-reactive T-cells and drug-specific T cells The initiation of ICIs can result in the abnormal activation of tissue-specific self-reactive T cells, potentially disrupting or compromising immune tolerance to renal self-antigens

And as demand continues to grow, what factors will determine whether patients can start and adhere to treatment long term

The two selected studies included a total of 208 patients, divided into intervention and control groups