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Additionally, SIRT3 deacetylates ceramide synthases, promoting ceramide accumulation and inhibiting complex III activity 184

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GHK-Cu and Anti-Inflammatory Pathway Research In murine lipopolysaccharide-induced acute lung injury models, GHK-Cu reduced inflammatory cell infiltration, suppressed NF-B and p38 MAPK activation, and lowered TNF-alpha and IL-6 levels compared to untreated groups findings of interest in inflammatory pathway research