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C.RoufogalisB
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They can cause permanent lung damage or lead to death
J Pharm Investig 53:5972 Kim J, Choi J, Kang H, Ahn J, Hutchings J, Niekerk CV, Kim J, Jeon Y, Nam K, Kim TH, Shin BS, Shin S (2023b) Safety, tolerability, pharmacokinetics, and metabolism of Telacebec (Q203) for the treatment of tuberculosis: a randomized, placebo-controlled, multiple ascending dose phase 1B trial
Mechanism of Action 5-Amino-1MQ inhibits NNMT, the enzyme that transfers a methyl group from SAM onto nicotinamide
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