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The EMPA-REG OUTCOME trial showed that empagliflozin markedly reduced the risk of CV mortality compared to that observed with placebo [8]
Larger meal volume and higher energy density slow gastric emptying, and when combined with GLP-1mediated slowing , this can amplify post-meal fullness, bloating, and discomfort. Carbonation and rapid eating Behaviors that can amplify bloating and gas include: Soda, sparkling water, or beer Drinking carbonated beverages with meals Eating quickly or while distracted Continuing to eat past early fullness Skipping pauses between bites, Does simethicone (Gas-X) help sulfur burps, bloating, or gas on GLP-1 medications
10.1038/nature05484 27 MurthyK
Hum Reprod 2012;27:3304-14
