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Tirzepatide is a 39 amino acid dual agonist that activates both GLP-1 and GIP receptors

Khavinson V, Diomede F, Mironova E, Linkova N, Trofimova S, Trubiani O, Caputi S, Sinjari B

The compounds mechanism of action makes it relevant to research on metabolic disorders, obesity, and energy metabolism

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The active region of TB-500 (the LKKTETQ sequence) binds G-actin monomers, preventing their polymerization into filamentous F-actin