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Common symptoms of a vitamin B12 deficiency include: Fatigue Shortness of breath Dizziness Unsteady movements Muscle weakness Irregular heartbeats Weight loss Numbness in the hands and feet Confusion and forgetfulness Pale or yellowed skin Because some people lack IF, getting vitamin B12 another way aside from through diet is necessary
In the 2025 head-to-head trial, around six percent of Mounjaro users and eight percent of Wegovy users stopped before completing the study because of side effects
Tsampasian V, Baral R, Chattopadhyay R et al (2021) The role of SGLT2 inhibitors in heart failure: a systematic review and meta-analysis
We used unpaired Students t test (two-tailed) and ANOVA to evaluate the statistical significance
The most robust clinical evidence arguably originates from the large cardiovascular outcomes trials (CVOTs) completed for most GLP-1 RAs, of which the latest showed a significant relative risk reduction (RRR) of 39% (HR) with once-weekly efpeglenatide on HF requiring hospitalisation, corroborating a meta-analysis which found a significant RRR across eight GLP-1 RA CVOTs of 11%
