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doi: 10.1210/en.2006-0073 45 BikbovaGOshitariTBikbovM
That said, more recent human trial data have begun to provide greater clarity regarding the translational potential of GLP-1 therapies in Alzheimers disease, helping to refine which aspects of these theoretical benefits may ultimately prove clinically meaningful
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The effect was very strong, nearly 30% reduction with metformin alone (first line treatment for type 2 diabetes) but an additional 40% with GLP-1 receptor agonists (eg, Wegovy [semaglutide, Novo Nordisk]), and unexpectedly it was effective for all asthma patients, including those with higher or lower BMI, and with all different types of asthma, Chloe I
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