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Two other pharmaceutical companies have their own oral GLP-1 drugs in the works: Orforglipron: Developed by Eli Lilly, its in Phase 3 clinical trials for treating type 2 diabetes and obesity, with an expected September 2025 completion

Enacted Budget Reconciliation Law: Public Law 119-21 (July 4, 2025)

Potential drawback: If nutrient intake becomes too restrictedespecially calcium, vitamin D, and proteinthis could negatively affect jawbone health, gums, and healing capacity

These new drugs like retatrutide may get more robust results for those who have already tried and failed

A clinic should review medical history, current medications, prior weight-loss attempts, health conditions, potential contraindications, and patient goals