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Injecting before bed, after dinner, means any nausea peaks during sleep
The other is still working through Phase 3 trials with regulatory submission likely a year or more away
The SMC has its own timeline and criteria, so availability in Scotland may differ from England and Wales even after a NICE decision
Retatrutide produces approximately 3.3 percentage points more weight loss than Tirzepatide in comparable populations (24.2 percent versus 20.9 percent), and the advantage grows over longer time periods because Retatrutide trials ended before reaching plateau
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