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Yes, semaglutide can make some people feel tired, though not everyone experiences this side effect
The upside is that there is less demand for crossing the intestinal barrier
[cited 2023 June 22] 12
How Much Protein Do You Need
(5.6) Hypersensitivity Reactions: There have been postmarketing reports of serious allergic and hypersensitivity reactions in patients treated with sitagliptin such as anaphylaxis, angioedema, and exfoliative skin conditions including Stevens-Johnson syndrome
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